Granite Male Enhancement Benefits 2020
Genes
there that's one thing but it's not giving me function I need to see that it's
either working normally or so I say that these are both ABC transporters so
they're linked actually at genetically because they they are derived they
believe to be derived from each other over evolution but they're also linked
within the cell membrane physically and here's a scaffolding protein that links
these two proteins together ABC c4 and CFTR and what I've said to you without
showing the data is that ABC C 4 transports cyclic AMP outside of the cell and
I'm going to show you why that's important in the context of cystic fibrosis so
this is just some data where I've been working on developing some novel ABC c4
inhibitors so I'm just calling it a b c c4 inhibitor because of confidentiality
reasons that I'm not showing you any structure but what we're able to do is we
have an assay that measures the amount of cyclic AMP that goes outside of an
epithelial cell and so that goes out of the cell but then what I have here on
the x-axis is increasing concentrations of my candidate compound this is
supposed to block ABC C 4 and it's supposed to block extracellular camp
transport that's why you see as we increase the dose there's less getting out
of the cell because the transporter is being blocked.
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